I develop and analyze mathematical models of biological and physical systems — turning differential equations, optimization, and data into insight about how living systems behave in space and time.


Explore

Research Areas

Spatial Metabolic ModelingFBA × reaction–diffusion

I built an equation-based framework that couples genome-scale flux balance analysis with reaction–diffusion PDEs to simulate how microbial communities grow and interact across space and time.

Disease Transmission ModelingODE & PDE epidemics

I build ODE and PDE models of infectious-disease dynamics — including reaction–diffusion and chemotaxis models of schistosomiasis transmission with 2D spatial simulation, and compartmental epidemic models such as SVEIR with vaccination.

Predictive Modeling for HealthChronic kidney disease

Working with virtual-care data, I applied predictive modeling to classify chronic kidney disease patients by their probability of stage degeneration from longitudinal eGFR trajectories. This co-authored work (Ashenafi et al.) was presented at the SIAM Mathematical Problems in Industry workshop.

Mathematical NeuroscienceRetinal modeling

As a co-author, I contributed to modeling the spatial dependence of rods and cones in the retina — using mathematical models to study the organization of photoreceptors and what it implies for vision.

Bayesian Inference & Complex SystemsUncertainty & collective behavior

I use Bayesian hierarchical modeling and MCMC to quantify uncertainty in experimental data (including pupillometry / psycholinguistics), and I study complex systems through agent-based models.


Output

Selected Publications

Preprint · bioRxiv · 2026

Equation-Based Integration of Flux Balance Analysis with Diffusion for Spatio-Temporal Simulation of Microbial Communities

F. Senya, R. Siegel, I. Dukovski, D. Bernstein

2024

Modeling Spatial Dependence of Rods and Cones in the Retina

N. Chicoine, C. Hammond, A. Iatcenko, L. Schneegans, F. Senya, L. Trinh, et al.

SIAM MPI

Analyzing the Influence of Virtual Care Management on Patient Health Outcomes and Risk-Stratifying Chronic Kidney Disease Patients for Stage Degeneration

Y. Ashenafi, D. Auddya, S. Chakraborty, Z. Dana, M. S. Ghumman, D. Lopez, et al. (incl. F. Senya)

Full list on Google Scholar